Novel 2,3-Dihydro-1H-pyrrolo[3,2,1-ij]quinazolin-1-ones: Synthesis and Biological Evaluation

Herein we describe the synthesis and evaluation of a series of novel 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinazolin-1-ones for in vitro cytotoxicity against three human cancer cell lines as well as for potential antimalarial activity against the chloroquine-sensitive strain 3D7 of Plasmodium falciparum....

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Bibliographic Details
Main Authors: Malose J. Mphahlele, Tebogo A. Khoza, Peaceful Mabeta
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/1/55