Proofreading through spatial gradients

Key enzymatic processes use the nonequilibrium error correction mechanism called kinetic proofreading to enhance their specificity. The applicability of traditional proofreading schemes, however, is limited because they typically require dedicated structural features in the enzyme, such as a nucleot...

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Bibliographic Details
Main Authors: Vahe Galstyan, Kabir Husain, Fangzhou Xiao, Arvind Murugan, Rob Phillips
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60415