Fabrication of Cell-Derived Biomimetic Drug Delivery System

Fabrication of Cell-Derived Biomimetic Drug Delivery System

Functional biomaterials that are capable of effectively carrying therapeutic agents and specifically delivering therapeutics to pathological sites have been widely investigated over decades. Recently, cellular carriers and cell derivative-based bio-hybrid delivery systems have drawn extensive attent...

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Main Authors: Zhou Yi, Wu Hong-Hui, Ping Yuan, Gao Jian-Qing
Format: Article
Language:English
Published: De Gruyter 2019-01-01
Series:Nanofabrication
Subjects:
cellular carriers
biomimetic materials
drug delivery
nanomedicine
cell membrane-coated nanoparticles
Online Access:https://doi.org/10.1515/nanofab-2019-0001
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spelling doaj-2606482cc76e4e278a56dc36e2c7b3eb2021-09-06T19:20:28ZengDe GruyterNanofabrication2299-680X2019-01-015111810.1515/nanofab-2019-0001nanofab-2019-0001Fabrication of Cell-Derived Biomimetic Drug Delivery SystemZhou Yi0Wu Hong-Hui1Ping Yuan2Gao Jian-Qing3Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou310058, ChinaInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou310058, ChinaInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou310058, ChinaInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou310058, China; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Hangzhou310058, P.R. ChinaFunctional biomaterials that are capable of effectively carrying therapeutic agents and specifically delivering therapeutics to pathological sites have been widely investigated over decades. Recently, cellular carriers and cell derivative-based bio-hybrid delivery systems have drawn extensive attention as a promising branch of therapeutic delivery systems, owing to their low immunogenicity and intriguing biomimetic capabilities. Various approaches for the fabrication of these biomimetic carriers have been developed, and some products have already been commercialized as well. In this review, we summarized various processing methods for engineering cell-derived biomimetic drug delivery systems, and discussed their future outlooks.https://doi.org/10.1515/nanofab-2019-0001cellular carriersbiomimetic materialsdrug deliverynanomedicinecell membrane-coated nanoparticles
collection DOAJ
language English
format Article
sources DOAJ
author Zhou Yi
Wu Hong-Hui
Ping Yuan
Gao Jian-Qing
spellingShingle Zhou Yi
Wu Hong-Hui
Ping Yuan
Gao Jian-Qing
Fabrication of Cell-Derived Biomimetic Drug Delivery System
Nanofabrication
cellular carriers
biomimetic materials
drug delivery
nanomedicine
cell membrane-coated nanoparticles
author_facet Zhou Yi
Wu Hong-Hui
Ping Yuan
Gao Jian-Qing
author_sort Zhou Yi
title Fabrication of Cell-Derived Biomimetic Drug Delivery System
title_short Fabrication of Cell-Derived Biomimetic Drug Delivery System
title_full Fabrication of Cell-Derived Biomimetic Drug Delivery System
title_fullStr Fabrication of Cell-Derived Biomimetic Drug Delivery System
title_full_unstemmed Fabrication of Cell-Derived Biomimetic Drug Delivery System
title_sort fabrication of cell-derived biomimetic drug delivery system
publisher De Gruyter
series Nanofabrication
issn 2299-680X
publishDate 2019-01-01
description Functional biomaterials that are capable of effectively carrying therapeutic agents and specifically delivering therapeutics to pathological sites have been widely investigated over decades. Recently, cellular carriers and cell derivative-based bio-hybrid delivery systems have drawn extensive attention as a promising branch of therapeutic delivery systems, owing to their low immunogenicity and intriguing biomimetic capabilities. Various approaches for the fabrication of these biomimetic carriers have been developed, and some products have already been commercialized as well. In this review, we summarized various processing methods for engineering cell-derived biomimetic drug delivery systems, and discussed their future outlooks.
topic cellular carriers
biomimetic materials
drug delivery
nanomedicine
cell membrane-coated nanoparticles
url https://doi.org/10.1515/nanofab-2019-0001
work_keys_str_mv AT zhouyi fabricationofcellderivedbiomimeticdrugdeliverysystem
AT wuhonghui fabricationofcellderivedbiomimeticdrugdeliverysystem
AT pingyuan fabricationofcellderivedbiomimeticdrugdeliverysystem
AT gaojianqing fabricationofcellderivedbiomimeticdrugdeliverysystem
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