Maternal Undernutrition Modulates Neonatal Rat Cerebrovascular Structure, Function, and Vulnerability to Mild Hypoxic-Ischemic Injury via Corticosteroid-Dependent and -Independent Mechanisms

Maternal Undernutrition Modulates Neonatal Rat Cerebrovascular Structure, Function, and Vulnerability to Mild Hypoxic-Ischemic Injury via Corticosteroid-Dependent and -Independent Mechanisms

The present study explored the hypothesis that an adverse intrauterine environment caused by maternal undernutrition (MUN) acted through corticosteroid-dependent and -independent mechanisms to program lasting functional changes in the neonatal cerebrovasculature and vulnerability to mild hypoxic-isc...

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Bibliographic Details
Main Authors: Patsy Naomi Franco, Lara M. Durrant, Coleen Doan, Desirelys Carreon, Alejandra Beltran, Amandine Jullienne, Andre Obenaus, William J. Pearce
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
cerebral arteries
fetal programming
myogenic reactivity
myosin
smooth muscle phenotype
Online Access:https://www.mdpi.com/1422-0067/22/2/680

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