Oleacein and Foam Cell Formation in Human Monocyte-Derived Macrophages: A Potential Strategy Against Early and Advanced Atherosclerotic Lesions

Oleacein and Foam Cell Formation in Human Monocyte-Derived Macrophages: A Potential Strategy Against Early and Advanced Atherosclerotic Lesions

Background: Oleacein is a secoiridoid group polyphenol found mostly in Olea europea L. and Ligustrum vulgare L. (Oleaceae). The aim of the present study was to investigate a potential role of oleacein in prevention of the foam cell formation. Materials and Methods: Oleacein was isolated from Ligustr...

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Bibliographic Details
Main Authors:	Agnieszka Filipek, Tomasz P. Mikołajczyk, Tomasz J. Guzik, Marek Naruszewicz
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Pharmaceuticals
Subjects:	oleacein human monocyte-derived macrophages (hMDMs) foam cell formation scavenger receptors (SR) JAK/STAT3 pathway atherosclerosis
Online Access:	https://www.mdpi.com/1424-8247/13/4/64

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