Shifting paradigms: The central role of microglia in Alzheimer's disease

Shifting paradigms: The central role of microglia in Alzheimer's disease

Recent human genetic studies have challenged long standing hypotheses about the chain of events in Alzheimer's disease (AD), as the identification of genetic risk factors in microglial genes supports a causative role for microglia in the disease. Parallel transcriptome and histology studies at...

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Bibliographic Details
Main Authors: Tina Schwabe, Karpagam Srinivasan, Herve Rhinn
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Microglia
APOE
TREM2
CD33
MS4A4A
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120302370

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