Protection by the gross saponins of Tribulus terrestris against cerebral ischemic injury in rats involves the NF-κB pathway

Protection by the gross saponins of Tribulus terrestris against cerebral ischemic injury in rats involves the NF-κB pathway

The aim of this study was to investigate whether the gross saponins of Tribulus terrestris (GSTT), a traditional Chinese herbal medicine, have neuroprotective effects on rats subjected to middle cerebral artery occlusion (MCAO), through nuclear factor-κB (NF-κB) pathway and inflammatory mediators. C...

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Bibliographic Details
Main Authors: En-ping Jiang, Hong Li, Jian-guang Chen, Shi-jie Yang
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Cerebral ischemia
Gross saponins of Tribulus terrestris
Traditional Chinese medicine
NF-κB
TNF-α
IL-1β
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383511000104

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