Functionalised mesoporous silica nanoparticles with excellent cytotoxicity against various cancer cells for pH-responsive and controlled drug delivery

Mesoporous silica nanoparticles (MSNs) modified with Pt and carboxyl groups were designed and the drug molecule-release behaviour was studied by loading cisplatin as a model anticancer drug. The MSNs had a high surface area (342 m2 g−1) and dual pores (3.3 and 33.4 nm) with a uniform size. The amoun...

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Bibliographic Details
Main Authors: Sung Soo Park, Moon Hyun Jung, Young-Shin Lee, Jae-Ho Bae, Sun-Hee Kim, Chang-Sik Ha
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Materials & Design
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127519306252