Cannabinoid Receptor Agonist Inhibits Atrial Electrical Remodeling in a Tachypaced Ex Vivo Rat Model

Cannabinoid Receptor Agonist Inhibits Atrial Electrical Remodeling in a Tachypaced Ex Vivo Rat Model

Introduction: Atrial fibrillation (AF) leads to rate-dependent atrial changes collectively defined as atrial remodelling (AR). Shortening of the atrial effective refractory period (AERP) and decreased conduction velocity are among the hallmarks of AR. Pharmacological strategies to inhibit AR, thereb...

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Bibliographic Details
Main Authors: Danielle I. Lee, Michael Murninkas, Sigal Elyagon, Yoram Etzion, Hope D. Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
atrial fibillation
atrial refractoriness
cannabinoid 1 and cannabinoid 2 receptor agonists
atrial remodeling
Cannabinoid
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.642398/full

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