A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma

Tumor lysis syndrome is an oncologic emergency that can present with variable symptoms and is truly a laboratory-based diagnosis without pathognomonic clinical findings. The classical teaching is to consider this diagnosis in cancer patients undergoing chemotherapy. We present the case of a 66-year-...

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Main Authors: Kathleen E. Kalmbach, Leena T. Rahmat, Justyna A. Wos, Nicholas J. Daniel
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2019-11-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/5cx862wh
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spelling doaj-25df56773eca4775aac18d716d383c862020-11-25T02:59:24ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2019-11-013410.5811/cpcem.2019.9.43770cpcem-03-398A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon AdenocarcinomaKathleen E. Kalmbach0Leena T. Rahmat1Justyna A. Wos2Nicholas J. Daniel3University of Massachusetts Medical School, Baystate Medical Center, Department of Emergency Medicine, Springfield, MassachusettsJohns Hopkins University, Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, Washington, District of ColumbiaSpringfield College, Department of Physician Assistant Studies, Springfield, MassachusettsUniversity of Massachusetts Medical School, Baystate Medical Center, Department of Emergency Medicine, Springfield, MassachusettsTumor lysis syndrome is an oncologic emergency that can present with variable symptoms and is truly a laboratory-based diagnosis without pathognomonic clinical findings. The classical teaching is to consider this diagnosis in cancer patients undergoing chemotherapy. We present the case of a 66-year-old female with newly diagnosed metastatic liver adenocarcinoma, not on chemotherapy, who was diagnosed with spontaneous tumor lysis syndrome. Cognizance of this syndrome and associated laboratory findings are paramount to diagnosis and rapid intervention.https://escholarship.org/uc/item/5cx862wh
collection DOAJ
language English
format Article
sources DOAJ
author Kathleen E. Kalmbach
Leena T. Rahmat
Justyna A. Wos
Nicholas J. Daniel
spellingShingle Kathleen E. Kalmbach
Leena T. Rahmat
Justyna A. Wos
Nicholas J. Daniel
A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma
Clinical Practice and Cases in Emergency Medicine
author_facet Kathleen E. Kalmbach
Leena T. Rahmat
Justyna A. Wos
Nicholas J. Daniel
author_sort Kathleen E. Kalmbach
title A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma
title_short A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma
title_full A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma
title_fullStr A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma
title_full_unstemmed A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma
title_sort rare oncologic emergency: spontaneous tumor lysis syndrome in metastatic colon adenocarcinoma
publisher eScholarship Publishing, University of California
series Clinical Practice and Cases in Emergency Medicine
issn 2474-252X
publishDate 2019-11-01
description Tumor lysis syndrome is an oncologic emergency that can present with variable symptoms and is truly a laboratory-based diagnosis without pathognomonic clinical findings. The classical teaching is to consider this diagnosis in cancer patients undergoing chemotherapy. We present the case of a 66-year-old female with newly diagnosed metastatic liver adenocarcinoma, not on chemotherapy, who was diagnosed with spontaneous tumor lysis syndrome. Cognizance of this syndrome and associated laboratory findings are paramount to diagnosis and rapid intervention.
url https://escholarship.org/uc/item/5cx862wh
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