The Inhibition Kinetics and Potential Anti-Migration Activity of NQO1 Inhibitory Coumarins on Cholangiocarcinoma Cells

Altered expression of a cytosolic flavoenzyme NAD(P)H:quinone oxidoreductase-1 (NQO1) has been seen in many human tumors. Its remarkable overexpression in cholangiocarcinoma (CCA; an aggressive malignancy of the biliary duct system) was associated with poor prognosis and short survival of the patien...

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Bibliographic Details
Main Authors: Tueanjai Khunluck MS, Veerapol Kukongviriyapan PhD, Laddawan Senggunprai PhD, Wutthipong Duangarsong MS, Auemduan Prawan PhD
Format: Article
Language:English
Published: SAGE Publishing 2019-02-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/1534735418820444