Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients

Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients

Background: Erythropoietin (Epo) is an important regulator of erythropoiesis, and controls proliferation and differentiation of both erythroid and non-erythroid tissues. Epo is actively synthesized by breast cells during lactation, and also plays a role in breast tissues promoting hypoxia-induced ca...

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Main Authors: Ferdinando Mannello, Laura Fabbri, Eleonora Ciandrini, Gaetana A. Tonti
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2008/812193
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spelling doaj-25d3053c2b9749aab844beeb64a417362020-11-24T23:19:42ZengHindawi LimitedCellular Oncology1570-58701875-86062008-01-01301516110.1155/2008/812193Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer PatientsFerdinando Mannello0Laura Fabbri1Eleonora Ciandrini2Gaetana A. Tonti3Institute of Histology and Laboratory Analysis, Faculty of Sciences and Technologies, University “Carlo Bo”, Urbino, ItalyInstitute of Histology and Laboratory Analysis, Faculty of Sciences and Technologies, University “Carlo Bo”, Urbino, ItalyInstitute of Histology and Laboratory Analysis, Faculty of Sciences and Technologies, University “Carlo Bo”, Urbino, ItalyInstitute of Histology and Laboratory Analysis, Faculty of Sciences and Technologies, University “Carlo Bo”, Urbino, ItalyBackground: Erythropoietin (Epo) is an important regulator of erythropoiesis, and controls proliferation and differentiation of both erythroid and non-erythroid tissues. Epo is actively synthesized by breast cells during lactation, and also plays a role in breast tissues promoting hypoxia-induced cancer initiation. Our aims are to perform an exploratory investigation on the Epo accumulation in breast secretions from healthy and cancer patients and its localization in breast cancer cells.http://dx.doi.org/10.1155/2008/812193
collection DOAJ
language English
format Article
sources DOAJ
author Ferdinando Mannello
Laura Fabbri
Eleonora Ciandrini
Gaetana A. Tonti
spellingShingle Ferdinando Mannello
Laura Fabbri
Eleonora Ciandrini
Gaetana A. Tonti
Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients
Cellular Oncology
author_facet Ferdinando Mannello
Laura Fabbri
Eleonora Ciandrini
Gaetana A. Tonti
author_sort Ferdinando Mannello
title Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients
title_short Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients
title_full Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients
title_fullStr Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients
title_full_unstemmed Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients
title_sort increased levels of erythropoietin in nipple aspirate fluid and in ductal cells from breast cancer patients
publisher Hindawi Limited
series Cellular Oncology
issn 1570-5870
1875-8606
publishDate 2008-01-01
description Background: Erythropoietin (Epo) is an important regulator of erythropoiesis, and controls proliferation and differentiation of both erythroid and non-erythroid tissues. Epo is actively synthesized by breast cells during lactation, and also plays a role in breast tissues promoting hypoxia-induced cancer initiation. Our aims are to perform an exploratory investigation on the Epo accumulation in breast secretions from healthy and cancer patients and its localization in breast cancer cells.
url http://dx.doi.org/10.1155/2008/812193
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AT laurafabbri increasedlevelsoferythropoietininnippleaspiratefluidandinductalcellsfrombreastcancerpatients
AT eleonoraciandrini increasedlevelsoferythropoietininnippleaspiratefluidandinductalcellsfrombreastcancerpatients
AT gaetanaatonti increasedlevelsoferythropoietininnippleaspiratefluidandinductalcellsfrombreastcancerpatients
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