Hepatoid Adenocarcinoma of the Urachus

Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microsco...

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Main Authors: Daniel Fernando Gallego, Carlos Muñoz, Carlos Andrés Jimenez, Edwin Carrascal
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2016/1871807
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spelling doaj-25bd8dea046743dc8248cbb4cc7239fb2020-11-25T01:02:11ZengHindawi LimitedCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/18718071871807Hepatoid Adenocarcinoma of the UrachusDaniel Fernando Gallego0Carlos Muñoz1Carlos Andrés Jimenez2Edwin Carrascal3Department of Pathology, University of Washington, Seattle, WA, USADepartment of Surgery, Mercy Medical Center, Baltimore, MD, USADepartment of Pathology, Fundacion Valle del Lili, Cali, ColombiaDepartment of Pathology, Universidad del Valle, Cali, ColombiaHepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.http://dx.doi.org/10.1155/2016/1871807
collection DOAJ
language English
format Article
sources DOAJ
author Daniel Fernando Gallego
Carlos Muñoz
Carlos Andrés Jimenez
Edwin Carrascal
spellingShingle Daniel Fernando Gallego
Carlos Muñoz
Carlos Andrés Jimenez
Edwin Carrascal
Hepatoid Adenocarcinoma of the Urachus
Case Reports in Pathology
author_facet Daniel Fernando Gallego
Carlos Muñoz
Carlos Andrés Jimenez
Edwin Carrascal
author_sort Daniel Fernando Gallego
title Hepatoid Adenocarcinoma of the Urachus
title_short Hepatoid Adenocarcinoma of the Urachus
title_full Hepatoid Adenocarcinoma of the Urachus
title_fullStr Hepatoid Adenocarcinoma of the Urachus
title_full_unstemmed Hepatoid Adenocarcinoma of the Urachus
title_sort hepatoid adenocarcinoma of the urachus
publisher Hindawi Limited
series Case Reports in Pathology
issn 2090-6781
2090-679X
publishDate 2016-01-01
description Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.
url http://dx.doi.org/10.1155/2016/1871807
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AT carlosmunoz hepatoidadenocarcinomaoftheurachus
AT carlosandresjimenez hepatoidadenocarcinomaoftheurachus
AT edwincarrascal hepatoidadenocarcinomaoftheurachus
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