Leptin and its cardiovascular effects: Focus on angiogenesis
Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentrati...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
Series: | Advanced Biomedical Research |
Subjects: | |
Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=79;epage=79;aulast=Tahergorabi |
id |
doaj-25b8ba9368564392b471c6ae4f9b115b |
---|---|
record_format |
Article |
spelling |
doaj-25b8ba9368564392b471c6ae4f9b115b2020-11-24T21:55:39ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752277-91752015-01-0141797910.4103/2277-9175.156526Leptin and its cardiovascular effects: Focus on angiogenesisZoya TahergorabiMajid KhazaeiLeptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentration of leptin significantly increases in obese individuals. In the present review, we give an introduction concerning leptin, its receptors, signaling pathways, and its effect on cardiovascular system, especially on angiogenesis.http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=79;epage=79;aulast=TahergorabiAngiogenesiscardiovascular diseaseleptinleptin resistance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zoya Tahergorabi Majid Khazaei |
spellingShingle |
Zoya Tahergorabi Majid Khazaei Leptin and its cardiovascular effects: Focus on angiogenesis Advanced Biomedical Research Angiogenesis cardiovascular disease leptin leptin resistance |
author_facet |
Zoya Tahergorabi Majid Khazaei |
author_sort |
Zoya Tahergorabi |
title |
Leptin and its cardiovascular effects: Focus on angiogenesis |
title_short |
Leptin and its cardiovascular effects: Focus on angiogenesis |
title_full |
Leptin and its cardiovascular effects: Focus on angiogenesis |
title_fullStr |
Leptin and its cardiovascular effects: Focus on angiogenesis |
title_full_unstemmed |
Leptin and its cardiovascular effects: Focus on angiogenesis |
title_sort |
leptin and its cardiovascular effects: focus on angiogenesis |
publisher |
Wolters Kluwer Medknow Publications |
series |
Advanced Biomedical Research |
issn |
2277-9175 2277-9175 |
publishDate |
2015-01-01 |
description |
Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentration of leptin significantly increases in obese individuals. In the present review, we give an introduction concerning leptin, its receptors, signaling pathways, and its effect on cardiovascular system, especially on angiogenesis. |
topic |
Angiogenesis cardiovascular disease leptin leptin resistance |
url |
http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=79;epage=79;aulast=Tahergorabi |
work_keys_str_mv |
AT zoyatahergorabi leptinanditscardiovasculareffectsfocusonangiogenesis AT majidkhazaei leptinanditscardiovasculareffectsfocusonangiogenesis |
_version_ |
1725861267906756608 |