Leptin and its cardiovascular effects: Focus on angiogenesis

Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentrati...

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Main Authors: Zoya Tahergorabi, Majid Khazaei
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=79;epage=79;aulast=Tahergorabi
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spelling doaj-25b8ba9368564392b471c6ae4f9b115b2020-11-24T21:55:39ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752277-91752015-01-0141797910.4103/2277-9175.156526Leptin and its cardiovascular effects: Focus on angiogenesisZoya TahergorabiMajid KhazaeiLeptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentration of leptin significantly increases in obese individuals. In the present review, we give an introduction concerning leptin, its receptors, signaling pathways, and its effect on cardiovascular system, especially on angiogenesis.http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=79;epage=79;aulast=TahergorabiAngiogenesiscardiovascular diseaseleptinleptin resistance
collection DOAJ
language English
format Article
sources DOAJ
author Zoya Tahergorabi
Majid Khazaei
spellingShingle Zoya Tahergorabi
Majid Khazaei
Leptin and its cardiovascular effects: Focus on angiogenesis
Advanced Biomedical Research
Angiogenesis
cardiovascular disease
leptin
leptin resistance
author_facet Zoya Tahergorabi
Majid Khazaei
author_sort Zoya Tahergorabi
title Leptin and its cardiovascular effects: Focus on angiogenesis
title_short Leptin and its cardiovascular effects: Focus on angiogenesis
title_full Leptin and its cardiovascular effects: Focus on angiogenesis
title_fullStr Leptin and its cardiovascular effects: Focus on angiogenesis
title_full_unstemmed Leptin and its cardiovascular effects: Focus on angiogenesis
title_sort leptin and its cardiovascular effects: focus on angiogenesis
publisher Wolters Kluwer Medknow Publications
series Advanced Biomedical Research
issn 2277-9175
2277-9175
publishDate 2015-01-01
description Leptin is an endocrine hormone synthesized by adipocytes. It plays a key role in the energy homeostasis in central and peripheral tissues and has additional roles are attributed to it, such as the regulation of reproduction, immune function, bone homeostasis, and angiogenesis. The plasma concentration of leptin significantly increases in obese individuals. In the present review, we give an introduction concerning leptin, its receptors, signaling pathways, and its effect on cardiovascular system, especially on angiogenesis.
topic Angiogenesis
cardiovascular disease
leptin
leptin resistance
url http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=79;epage=79;aulast=Tahergorabi
work_keys_str_mv AT zoyatahergorabi leptinanditscardiovasculareffectsfocusonangiogenesis
AT majidkhazaei leptinanditscardiovasculareffectsfocusonangiogenesis
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