Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro

Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro

BACKGROUND: Macrolide antibiotics such as erythromycin and roxithromycin (RXM) have an anti-inflammatory effect that may account for their clinical benefit in the treatment of chronic airway inflammatory diseases. However, the precise mechanism of this anti-inflammatory effect is not well understood...

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Bibliographic Details
Main Authors: Ken-Ichi Kanai, Kazuhito Asano, Tadashi Hisamitsu, Harumi Suzaki
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Mediators of Inflammation
Subjects:
Macrolide antibiotic
Roxithromycin
Neutrophil
Matrix metalloproteinase-9
Suppression.
Online Access:http://dx.doi.org/10.1080/09629350400008810

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