Designing Lead Optimisation of MMP-12 Inhibitors

The design of new molecules with desired properties is in general a very difficult problem, involving heavy experimentation with high investment of resources and possible negative impact on the environment. The standard approach consists of iteration among formulation, synthesis, and testing cycles,...

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Bibliographic Details
Main Authors: Matteo Borrotti, Davide De March, Debora Slanzi, Irene Poli
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2014/258627