Electrical coupling regulates layer 1 interneuron microcircuit formation in the neocortex

Electrical and chemical synapses coexist in neocortex interneurons. Here, Yao et al. show that during development, electrical and GABAergic chemical synapses form at the same time, and that this coupling synchronizes firing between layer 1 interneurons.

Bibliographic Details
Main Authors: Xing-Hua Yao, Min Wang, Xiang-Nan He, Fei He, Shu-Qing Zhang, Wenlian Lu, Zi-Long Qiu, Yong-Chun Yu
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12229
Description
Summary:Electrical and chemical synapses coexist in neocortex interneurons. Here, Yao et al. show that during development, electrical and GABAergic chemical synapses form at the same time, and that this coupling synchronizes firing between layer 1 interneurons.
ISSN:2041-1723