Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells.

Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells.

Artonin E is a prenylated flavonoid isolated from the stem bark of Artocarpus elasticus Reinw.(Moraceae). This study aimed to investigate the apoptotic mechanisms induced by artonin E in a metastatic human ovarian cancer cell line SKOV-3 in vitro. MTT assay, clonogenic assay, acridine orange and pro...

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Bibliographic Details
Main Authors: Mashitoh Abd Rahman, Faiqah Ramli, Hamed Karimian, Firouzeh Dehghan, Noraziah Nordin, Hapipah Mohd Ali, Syam Mohan, Najihah Mohd Hashim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4809498?pdf=render

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http://europepmc.org/articles/PMC4809498?pdf=render

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