One-pot multistep mechanochemical synthesis of fluorinated pyrazolones

One-pot multistep mechanochemical synthesis of fluorinated pyrazolones

Solventless mechanochemical synthesis represents a technique with improved sustainability metrics compared to solvent-based processes. Herein, we describe a methodical process to run one solventless reaction directly into another through multistep mechanochemistry, effectively amplifying the solvent...

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Bibliographic Details
Main Authors: Joseph L. Howard, William Nicholson, Yerbol Sagatov, Duncan L. Browne
Format: Article
Language:English
Published: Beilstein-Institut 2017-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
fluorination
heterocycles
mechanochemistry
multistep
solid-state synthesis
Online Access:https://doi.org/10.3762/bjoc.13.189

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