Cobalt chloride compromises transepithelial barrier properties of CaCo-2 BBe human gastrointestinal epithelial cell layers
Abstract Background Elevation of the transcription factor HIF-1 is a prominent mediator of not only processes that accompany hypoxia, but also the tumor microenvironment and tissue regeneration. This study uses mediators of “chemical hypoxia” to ask the question whether HIF-1α elevation in a healthy...
Main Authors: | K. M. DiGuilio, M. C. Valenzano, E. Rybakovsky, J. M. Mullin |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-01-01
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Series: | BMC Gastroenterology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12876-017-0731-5 |
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