Synthetic and therapeutic potential of 4-thiazolidinone and its analogs

Past researches on 4-thiazolidinone nucleus have revealed the prominent potential of derivatives containing this nucleus to be developed as a potent therapeutic agent. Because of these biological activities, their structure-activity relationship has created an interest for medicinal chemist...

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Main Author: Agrawal, Neetu
Format: Article
Language:English
Published: Growing Science 2021-01-01
Series:Current Chemistry Letters
Online Access:http://www.growingscience.com/ccl/Vol10/ccl_2020_18.pdf
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spelling doaj-25632570ca95464e9914e44b5831e1522021-03-31T10:19:35ZengGrowing ScienceCurrent Chemistry Letters1927-72961927-730X2021-01-0111913810.5267/j.ccl.2020.11.002Synthetic and therapeutic potential of 4-thiazolidinone and its analogsAgrawal, Neetu Past researches on 4-thiazolidinone nucleus have revealed the prominent potential of derivatives containing this nucleus to be developed as a potent therapeutic agent. Because of these biological activities, their structure-activity relationship has created an interest for medicinal chemists leading to the discovery of a number of lead molecules. This review highlights the routes for its synthesis and summarizes the past and recent studies on its biological activities to guide the medicinal chemists working on this nucleus in the development of clinically viable drugs.http://www.growingscience.com/ccl/Vol10/ccl_2020_18.pdf
collection DOAJ
language English
format Article
sources DOAJ
author Agrawal, Neetu
spellingShingle Agrawal, Neetu
Synthetic and therapeutic potential of 4-thiazolidinone and its analogs
Current Chemistry Letters
author_facet Agrawal, Neetu
author_sort Agrawal, Neetu
title Synthetic and therapeutic potential of 4-thiazolidinone and its analogs
title_short Synthetic and therapeutic potential of 4-thiazolidinone and its analogs
title_full Synthetic and therapeutic potential of 4-thiazolidinone and its analogs
title_fullStr Synthetic and therapeutic potential of 4-thiazolidinone and its analogs
title_full_unstemmed Synthetic and therapeutic potential of 4-thiazolidinone and its analogs
title_sort synthetic and therapeutic potential of 4-thiazolidinone and its analogs
publisher Growing Science
series Current Chemistry Letters
issn 1927-7296
1927-730X
publishDate 2021-01-01
description Past researches on 4-thiazolidinone nucleus have revealed the prominent potential of derivatives containing this nucleus to be developed as a potent therapeutic agent. Because of these biological activities, their structure-activity relationship has created an interest for medicinal chemists leading to the discovery of a number of lead molecules. This review highlights the routes for its synthesis and summarizes the past and recent studies on its biological activities to guide the medicinal chemists working on this nucleus in the development of clinically viable drugs.
url http://www.growingscience.com/ccl/Vol10/ccl_2020_18.pdf
work_keys_str_mv AT agrawalneetu syntheticandtherapeuticpotentialof4thiazolidinoneanditsanalogs
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