FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA

Objective: To find out association between peptic ulcer (PU) and high risk predictors like sex, smoking, use of non-streoidal anti-inflammatory drugs (NSAIDs) and H. pylori infection. Methodology: This retrospective study was conducted at the medical unit of the Saidu Sharif Swat, months from Octob...

Full description

Bibliographic Details
Main Authors: Niaz Ali, Abid Ullah, sohail Akhtar, Syed Wadood Ali Shah, Muhammad Junaid
Format: Article
Language:English
Published: Khyber Medical University 2013-03-01
Series:Khyber Medical University Journal
Online Access:https://www.kmuj.kmu.edu.pk/article/view/11029
id doaj-2560be53d6324cea928613b1e1fc1185
record_format Article
spelling doaj-2560be53d6324cea928613b1e1fc11852020-11-24T20:55:57ZengKhyber Medical UniversityKhyber Medical University Journal2305-26432305-26512013-03-0151182111029FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWANiaz Ali0Abid Ullah1sohail Akhtar2Syed Wadood Ali Shah3Muhammad Junaid4IBMS, Department of PharmacologyDepartment of Pharmacy, University of MalakandDepartment of Statistics, University of MalakandDepartment of phramacy, university of MalakandDepartment of pharmacy, university of malakandObjective: To find out association between peptic ulcer (PU) and high risk predictors like sex, smoking, use of non-streoidal anti-inflammatory drugs (NSAIDs) and H. pylori infection. Methodology: This retrospective study was conducted at the medical unit of the Saidu Sharif Swat, months from October 2011 to January 2012 on 72 adult endoscopically proven patients of PU having previous history of smoking, ingestion of NSAIDs and presence of H. pylori infection on Urease test. Data was collected on structured proforma including patients demographics, clinical presentation and major risk predictors. Relevant statistics were carried out to see an association of these high risk predictors with PU. Results: PU was more prevalent in age of 21-40 years with associated predictors like smoking, use of NSAIDs and H. pylori infection. Of the 72 patients, 68.05% patients were male and 31.94% were female. Smoking has a high incidence of 52.63%, and the use of NSAIDs shared 31.03% in patients of age 31-40 years. H. pylori infection was having 30% and 32% incidence in patients of groups 31-40 and 41-50 years, respectively. Smoking has a high Neg. R2 (26.82%) while for use of NSAIDs is 7.42%. Smoking + sex + NSAIDs + H. pylori have Neg. R2 score 48.09% (P > 0.05). Conclusion: Smoking, sex, use of NSAIDs and H. pylori infection carries strong association in patients having peptic ulcer. As smoking alone is found to have stronger association with PU, public awareness program regarding hazards of smoking is recommended. Key Words: Smoking, NSAIDs, Peptic ulcer, H. Pylori.https://www.kmuj.kmu.edu.pk/article/view/11029
collection DOAJ
language English
format Article
sources DOAJ
author Niaz Ali
Abid Ullah
sohail Akhtar
Syed Wadood Ali Shah
Muhammad Junaid
spellingShingle Niaz Ali
Abid Ullah
sohail Akhtar
Syed Wadood Ali Shah
Muhammad Junaid
FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA
Khyber Medical University Journal
author_facet Niaz Ali
Abid Ullah
sohail Akhtar
Syed Wadood Ali Shah
Muhammad Junaid
author_sort Niaz Ali
title FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA
title_short FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA
title_full FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA
title_fullStr FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA
title_full_unstemmed FACTORS ASSOCIATED WITH PEPTIC ULCER: A SINGLE CENTRE EXPERIENCE AT TERTIARY CARE HOSPITAL OF KHYBER PAKHTUNKHWA
title_sort factors associated with peptic ulcer: a single centre experience at tertiary care hospital of khyber pakhtunkhwa
publisher Khyber Medical University
series Khyber Medical University Journal
issn 2305-2643
2305-2651
publishDate 2013-03-01
description Objective: To find out association between peptic ulcer (PU) and high risk predictors like sex, smoking, use of non-streoidal anti-inflammatory drugs (NSAIDs) and H. pylori infection. Methodology: This retrospective study was conducted at the medical unit of the Saidu Sharif Swat, months from October 2011 to January 2012 on 72 adult endoscopically proven patients of PU having previous history of smoking, ingestion of NSAIDs and presence of H. pylori infection on Urease test. Data was collected on structured proforma including patients demographics, clinical presentation and major risk predictors. Relevant statistics were carried out to see an association of these high risk predictors with PU. Results: PU was more prevalent in age of 21-40 years with associated predictors like smoking, use of NSAIDs and H. pylori infection. Of the 72 patients, 68.05% patients were male and 31.94% were female. Smoking has a high incidence of 52.63%, and the use of NSAIDs shared 31.03% in patients of age 31-40 years. H. pylori infection was having 30% and 32% incidence in patients of groups 31-40 and 41-50 years, respectively. Smoking has a high Neg. R2 (26.82%) while for use of NSAIDs is 7.42%. Smoking + sex + NSAIDs + H. pylori have Neg. R2 score 48.09% (P > 0.05). Conclusion: Smoking, sex, use of NSAIDs and H. pylori infection carries strong association in patients having peptic ulcer. As smoking alone is found to have stronger association with PU, public awareness program regarding hazards of smoking is recommended. Key Words: Smoking, NSAIDs, Peptic ulcer, H. Pylori.
url https://www.kmuj.kmu.edu.pk/article/view/11029
work_keys_str_mv AT niazali factorsassociatedwithpepticulcerasinglecentreexperienceattertiarycarehospitalofkhyberpakhtunkhwa
AT abidullah factorsassociatedwithpepticulcerasinglecentreexperienceattertiarycarehospitalofkhyberpakhtunkhwa
AT sohailakhtar factorsassociatedwithpepticulcerasinglecentreexperienceattertiarycarehospitalofkhyberpakhtunkhwa
AT syedwadoodalishah factorsassociatedwithpepticulcerasinglecentreexperienceattertiarycarehospitalofkhyberpakhtunkhwa
AT muhammadjunaid factorsassociatedwithpepticulcerasinglecentreexperienceattertiarycarehospitalofkhyberpakhtunkhwa
_version_ 1716791392414466048