Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins

Macroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathologi...

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Main Authors:	Thierry Arnould, Patricia Renard, Anaïs Wanet, Kayleen Vannuvel, Sébastien Michel, Stéphane Demine
Format:	Article
Language:	English
Published:	MDPI AG 2012-06-01
Series:	Cells
Subjects:	mitophagy lipophagy specific autophagy organelle dysfunction triglyceride accumulation protein secretion
Online Access:	http://www.mdpi.com/2073-4409/1/2/168

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spelling	doaj-255d259c6add4bb68cb3d8a591ac28962020-11-24T23:31:00ZengMDPI AGCells2073-44092012-06-011216820310.3390/cells1020168Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of ProteinsThierry ArnouldPatricia RenardAnaïs WanetKayleen VannuvelSébastien MichelStéphane DemineMacroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathological situations. In this review, we discuss some of the recently discovered mechanisms involved in specific and unspecific autophagy related to mitochondrial dysfunction and organelle degradation, lipid metabolism and lipophagy as well as recent findings and evidence that link autophagy to unconventional protein secretion.http://www.mdpi.com/2073-4409/1/2/168mitophagylipophagyspecific autophagyorganelle dysfunctiontriglyceride accumulationprotein secretion
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Thierry Arnould Patricia Renard Anaïs Wanet Kayleen Vannuvel Sébastien Michel Stéphane Demine
spellingShingle	Thierry Arnould Patricia Renard Anaïs Wanet Kayleen Vannuvel Sébastien Michel Stéphane Demine Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins Cells mitophagy lipophagy specific autophagy organelle dysfunction triglyceride accumulation protein secretion
author_facet	Thierry Arnould Patricia Renard Anaïs Wanet Kayleen Vannuvel Sébastien Michel Stéphane Demine
author_sort	Thierry Arnould
title	Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins
title_short	Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins
title_full	Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins
title_fullStr	Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins
title_full_unstemmed	Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins
title_sort	macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins
publisher	MDPI AG
series	Cells
issn	2073-4409
publishDate	2012-06-01
description	Macroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathological situations. In this review, we discuss some of the recently discovered mechanisms involved in specific and unspecific autophagy related to mitochondrial dysfunction and organelle degradation, lipid metabolism and lipophagy as well as recent findings and evidence that link autophagy to unconventional protein secretion.
topic	mitophagy lipophagy specific autophagy organelle dysfunction triglyceride accumulation protein secretion
url	http://www.mdpi.com/2073-4409/1/2/168
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Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins

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