A simple method to improve the dissolution of repaglinide and exploration of its mechanism

In the present study, a simple and rapid method was developed to improve the in vitro dissolution of repaglinide, an oral antidiabetic drug, which was based on addition of meglumine in 50% (v/v) ethanol to dissolve repaglinide, and the drug dissolved in meglumine/50% ethanol was used directly with a...

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Bibliographic Details
Main Authors: Zhaolu Zhu, Tianzhi Yang, Yanan Zhao, Nannan Gao, Donglei Leng, Pingtian Ding
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087614000373