Effect of the XRCC1 codon 399 polymorphism on the repair of vinyl chloride metabolite-induced DNA damage

Effect of the XRCC1 codon 399 polymorphism on the repair of vinyl chloride metabolite-induced DNA damage

<b>Background: </b> Recent epidemiologic evidence suggests that the common polymorphism at amino acid residue 399 of the x-ray cross complementing-1 (XRCC1) protein, a key component of the base excision repair (BER) pathway for DNA damage, plays a significant role in the genetic variabil...

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Bibliographic Details
Main Authors: Li Yongliang, Long Changmin, Lin George, Marion Marie-Jeanne, Freyer Greg, Santella Regina, Brandt-Rauf Paul
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Journal of Carcinogenesis
Subjects:
Base excision repair
chloroethylene oxide
etheno adducts
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2009;volume=8;issue=1;spage=14;epage=14;aulast=Li

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