Transmission selects for HIV-1 strains of intermediate virulence: a modelling approach.

Transmission selects for HIV-1 strains of intermediate virulence: a modelling approach.

Recent data shows that HIV-1 is characterised by variation in viral virulence factors that is heritable between infections, which suggests that viral virulence can be naturally selected at the population level. A trade-off between transmissibility and duration of infection appears to favour viruses...

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Bibliographic Details
Main Authors: George Shirreff, Lorenzo Pellis, Oliver Laeyendecker, Christophe Fraser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22022243/?tool=EBI

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