Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease

Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease

There is a pressing need to develop representative organ-like platforms recapitulating complex in vivo phenotypes to study human development and disease in vitro. Here the authors present a method to generate human heart organoids by self-assembly using pluripotent stem cells, compare these to age-m...

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Bibliographic Details
Main Authors: Yonatan R. Lewis-Israeli, Aaron H. Wasserman, Mitchell A. Gabalski, Brett D. Volmert, Yixuan Ming, Kristen A. Ball, Weiyang Yang, Jinyun Zou, Guangming Ni, Natalia Pajares, Xanthippi Chatzistavrou, Wen Li, Chao Zhou, Aitor Aguirre
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25329-5

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