Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease
There is a pressing need to develop representative organ-like platforms recapitulating complex in vivo phenotypes to study human development and disease in vitro. Here the authors present a method to generate human heart organoids by self-assembly using pluripotent stem cells, compare these to age-m...
Full description
Bibliographic Details
| Main Authors: |
Yonatan R. Lewis-Israeli,
Aaron H. Wasserman,
Mitchell A. Gabalski,
Brett D. Volmert,
Yixuan Ming,
Kristen A. Ball,
Weiyang Yang,
Jinyun Zou,
Guangming Ni,
Natalia Pajares,
Xanthippi Chatzistavrou,
Wen Li,
Chao Zhou,
Aitor Aguirre |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2021-08-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-021-25329-5
|
|---|
