Geometric de-noising of protein-protein interaction networks.

Understanding complex networks of protein-protein interactions (PPIs) is one of the foremost challenges of the post-genomic era. Due to the recent advances in experimental bio-technology, including yeast-2-hybrid (Y2H), tandem affinity purification (TAP) and other high-throughput methods for protein...

Full description

Bibliographic Details
Main Authors: Oleksii Kuchaiev, Marija Rasajski, Desmond J Higham, Natasa Przulj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19662157/?tool=EBI