Associations between Pregnane X Receptor and Breast Cancer Growth and Progression

Associations between Pregnane X Receptor and Breast Cancer Growth and Progression

Pregnane X receptor (PXR, NR1I2) is a member of the ligand-activated nuclear receptor superfamily. This receptor is promiscuous in its activation profile and is responsive to a broad array of both endobiotic and xenobiotic ligands. PXR is involved in pivotal cellular detoxification processes to incl...

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Bibliographic Details
Main Authors: Bradley A. Creamer, Shelly N. B. Sloan, Jennifer F. Dennis, Robert Rogers, Sidney Spencer, Andrew McCuen, Purnadeo Persaud, Jeff L. Staudinger
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
nuclear receptor
pregnane X receptor
xenobiotics
tumorigenesis
breast cancer
Online Access:https://www.mdpi.com/2073-4409/9/10/2295

Internet

https://www.mdpi.com/2073-4409/9/10/2295

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