Antioxidant, anti-inflammatory and hepatoprotective activities of Terminalia bellirica and its bioactive component ellagic acid against diclofenac induced oxidative stress and hepatotoxicity
Long term usage and overdose of diclofenac (DCF), an anti-inflammatory drug is known to cause oxidative stress and liver injury. The present study reports the antioxidant, anti-inflammatory and hepatoprotective activities of Terminalia bellirica (Tb) fruit aqueous and ethyl acetate extracts and its...
Main Authors: | Ashutosh Gupta, Ramesh Kumar, Risha Ganguly, Amit Kumar Singh, Harvesh Kumar Rana, Abhay Kumar Pandey |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
|
Series: | Toxicology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750020304522 |
Similar Items
-
Chemical composition, antioxidant and hepatoprotective activities of methanol extracts from leaves of Terminalia bellirica and Terminalia sericea (Combretaceae)
by: Mansour Sobeh, et al.
Published: (2019-02-01) -
Terminalia bellirica Extract Inhibits Low-Density Lipoprotein Oxidation and Macrophage Inflammatory Response in Vitro
by: Miori Tanaka, et al.
Published: (2016-06-01) -
Terminalia bellirica fruit extracts: in-vitro antibacterial activity against selected multidrug-resistant bacteria, radical scavenging activity and cytotoxicity study on BHK-21 cells
by: M. Priyanga Jayamal Dharmaratne, et al.
Published: (2018-12-01) -
Diclofenac impairs autophagic flux via oxidative stress and lysosomal dysfunction: Implications for hepatotoxicity
by: Seung-Hwan Jung, et al.
Published: (2020-10-01) -
A randomized, double-blind, placebo-, and positive-controlled clinical pilot study to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with hyperuricemia
by: Usharani P, et al.
Published: (2016-06-01)