Single-Cell RNA-Seq Analysis Reveals Microenvironmental Infiltration of Plasma Cells and Hepatocytic Prognostic Markers in HCC With Cirrhosis

Single-Cell RNA-Seq Analysis Reveals Microenvironmental Infiltration of Plasma Cells and Hepatocytic Prognostic Markers in HCC With Cirrhosis

The occurrence of hepatocellular carcinoma (HCC) related to liver cirrhosis is mostly accompanied by extensive immune infiltration. To reveal the infiltration immune cells landscape, single-cell RNA sequencing data from the healthy donor (HD), patients with liver cirrhosis (LC) and HCC were collecte...

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Bibliographic Details
Main Authors: Siwen Zhang, Zhenhao Liu, Dan Wu, Lanming Chen, Lu Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
single-cell RNA-seq
hepatocellular carcinoma
liver cirrhosis
plasma cells
humoral immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.596318/full

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