Mechanistic studies of antibody mediated clearance of tau aggregates using an ex vivo brain slice model
Recent studies have shown that immunotherapy clears amyloid beta (A) plaques and reduces A levels in mouse models of Alzheimer’s disease (AD), as well as in AD patients. Tangle pathology is also relevant for the neurodegeneration in AD, and our studies have shown that active immunization with an A...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2011-10-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00059/full |