Oxidative stress and its impact on biochemical parameters of patients with hepato-cellular affections
Oxidative stress as a factor that is disrupting oxidant / antioxidant balance of the organism at some level, is an important pathogenetic mechanism that is involved in the occurrence and development of liver disease. The present study aimed to determine markers of oxidative stress in patients of dif...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Alexandru Ioan Cuza" University of Iași
2012-12-01
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| Series: | Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara |
| Online Access: | http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/1006 |
| Summary: | Oxidative stress as a factor that is disrupting oxidant / antioxidant balance of the organism at some
level, is an important pathogenetic mechanism that is involved in the occurrence and development of liver disease. The
present study aimed to determine markers of oxidative stress in patients of different ages diagnosed with acute viral
hepatitis B, acute hepatitis C virus and liver cirrhosis hospitalized in the Department of Gastroenterology belonging
County Hospital "Mavromati" Botosani. Both superoxide - dismutase and malon-dialdehide showed significant increases
in enzymatic activity in patients with acute viral hepatitis B and C, while in the case of liver cirrhosis, antioxidative
defense enzyme system was found more depressed. |
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| ISSN: | 1582-3571 2248-3276 |