SNHG1 knockdown upregulates miR-376a and downregulates FOXK1/Snail axis to prevent tumor growth and metastasis in HCC
Long non-coding RNAs (lncRNAs), microRNAs (miRNAs or miRs), and genes are emerging players in cancer progression. In the present study, we explored the roles and interactions of oncogenic lncRNA small nucleolar RNA host gene 1 (SNHG1), miR-376, forkhead box protein K1 (FOXK1), and Snail in hepatocel...
Main Authors: | Fanzhi Meng, Jinghua Liu, Tao Lu, Lanlan Zang, Jing Wang, Qiang He, Aijin Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-06-01
|
Series: | Molecular Therapy: Oncolytics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2372770521000206 |
Similar Items
-
Snail/FOXK1/Cyr61 Signaling Axis Regulates the Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
by: Xiaoting Huang, et al.
Published: (2018-05-01) -
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma
by: Xiaozhi Li, et al.
Published: (2019-02-01) -
Prognostic Value of the FOXK Family Expression in Patients with Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiotherapy
by: Zhang Y, et al.
Published: (2020-09-01) -
The lncRNA XIST promotes colorectal cancer cell growth through regulating the miR-497-5p/FOXK1 axis
by: Nan Wang, et al.
Published: (2020-12-01) -
Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor
by: Zehavi Liron, et al.
Published: (2012-07-01)