Enzyme systems activity and connective tissue metabolism as pathogenetic factors of spinal stenosis (literature review)

Enzyme systems activity and connective tissue metabolism as pathogenetic factors of spinal stenosis (literature review)

A characteristic feature of stenosis process of the spinal canal is the destruction of elastin and fibrosis of the extracellular matrix, as well as hypertrophy and ossification of the ligamentum flavum. Proven participation in these processes of genes CTGF, PDGF-BB, TGF-ß, Il-6, TNF-α, MMPs, TIMPs,...

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Bibliographic Details
Main Authors: L. V. Rodionova, V. A. Sorokovikov, Z. V. Koschkareva
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2015-02-01
Series:Acta Biomedica Scientifica
Subjects:
lumbar spine stenosis
ligamentum flavum
n-acetyltransferase
inflammatory cytokines
n-ацетилтрансфераза
Online Access:https://www.actabiomedica.ru/jour/article/view/16

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