Direct amidation of non-activated phenylacetic acid and benzylamine derivatives catalysed by NiCl2

This paper describes an eco-friendly and efficient direct amidation of benzylamine and phenylacetic acid derivatives in the presence of 10 mol% NiCl2 as catalyst without any drying agent. For the different phenylacetic acid and benzylamine derivatives, the direct catalysed amidation gave moderate-to...

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Bibliographic Details
Main Authors: Lidan Cheng, Xiaoping Ge, Longjiang Huang
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171870

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