Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran

Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran

Abstract Background Fluoroquinolones are broad-spectrum antibiotics that are recommended, and increasingly important, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Resistance to fluoroquinolones is caused by mutations in the Quinolone Resistance Determining Region (QRDR) of gyrA an...

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Bibliographic Details
Main Authors: Mahdieh Sayadi, Hosna Zare, Saeed Amel Jamedar, Seyed Isaac Hashemy, Zahra Meshkat, Saman Soleimanpour, Sven Hoffner, Kiarash Ghazvini
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Infectious Diseases
Subjects:
Mycobacterium tuberculosis
MDR-TB
Resistance
XDR-TB
Fluoroquinolone
Online Access:http://link.springer.com/article/10.1186/s12879-020-05112-5

Internet

http://link.springer.com/article/10.1186/s12879-020-05112-5

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