Assessment of intratumor hypoxia by integrated 18F-FDG PET / perfusion CT in a liver tumor model.

Assessment of intratumor hypoxia by integrated 18F-FDG PET / perfusion CT in a liver tumor model.

Hypoxia in solid tumors occurs when metabolic demands in tumor cells surpass the delivery of oxygenated blood. We hypothesize that the 18F-fluorodeoxyglucose (18F-FDG) metabolism and tumor blood flow mismatch would correlate with tumor hypoxia.Liver perfusion computed tomography (CT) and 18F-FDG pos...

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Bibliographic Details
Main Authors: Yong Wang, Errol Stewart, Lise Desjardins, Jennifer Hadway, Laura Morrison, Cathie Crukley, Ting-Yim Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5338799?pdf=render

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