Non-Small-Cell Lung Cancer-Sensitive Detection of the p.Thr790Met EGFR Alteration by Preamplification before PNA-Mediated PCR Clamping and Pyrosequencing

Non-Small-Cell Lung Cancer-Sensitive Detection of the p.Thr790Met EGFR Alteration by Preamplification before PNA-Mediated PCR Clamping and Pyrosequencing

Targeted therapies and, more precisely, <i>EGFR</i> tyrosine kinase inhibitors (TKIs) have been a major improvement in the therapeutic management of <i>EGFR</i>-mutated non-small-cell lung cancers (NSCLCs). Earlier administration of these TKIs throughout tumor progression is...

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Bibliographic Details
Main Authors: Amandine Billaud, Veronique Verriele, Jonathan Dauvé, Louise-Marie Chevalier, Alain Morel
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Diagnostics
Subjects:
peptide nucleic acid
PNA
preamplification
non-small-cell lung cancer
NSCLC
EGFR
Online Access:https://www.mdpi.com/2075-4418/10/8/527

Internet

https://www.mdpi.com/2075-4418/10/8/527

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