PhylOTU: a high-throughput procedure quantifies microbial community diversity and resolves novel taxa from metagenomic data.

PhylOTU: a high-throughput procedure quantifies microbial community diversity and resolves novel taxa from metagenomic data.

Microbial diversity is typically characterized by clustering ribosomal RNA (SSU-rRNA) sequences into operational taxonomic units (OTUs). Targeted sequencing of environmental SSU-rRNA markers via PCR may fail to detect OTUs due to biases in priming and amplification. Analysis of shotgun sequenced env...

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Bibliographic Details
Main Authors: Thomas J Sharpton, Samantha J Riesenfeld, Steven W Kembel, Joshua Ladau, James P O'Dwyer, Jessica L Green, Jonathan A Eisen, Katherine S Pollard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283775/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283775/pdf/?tool=EBI

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