Implantable sandwich PHBHHx film for burst-free controlled delivery of thymopentin peptide

Sustained release and non-parental formulations of peptides and protein drugs are highly desirable because of enhanced therapeutic effects as well as improved patient compliance. This is especially true for small peptides such as thymopentin (TP5). To this end, implantable sandwich poly (hydroxybuty...

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Bibliographic Details
Main Authors: Ke Peng, Chengyu Wu, Guoxu Wei, Jinghui Jiang, Zhirong Zhang, Xun Sun
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383517306160