A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles.

A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles.

Recent large-scale genome-wide association studies have identified tens of genetic loci robustly associated with Body Mass Index (BMI). Gene expression profiles were also found to be associated with BMI. However, accurate prediction of obesity risk utilizing genetic data remains challenging. In a co...

Full description

Bibliographic Details
Main Authors: Paule V Joseph, Yupeng Wang, Nicolaas H Fourie, Wendy A Henderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5993110?pdf=render

Similar Items

Similar Items