Hallmarks of epithelial to mesenchymal transition are detectable in Crohn's disease associated intestinal fibrosis

Hallmarks of epithelial to mesenchymal transition are detectable in Crohn's disease associated intestinal fibrosis

Abstract BackgroundIntestinal fibrosis and subsequent stricture formation represent frequent complications of Crohn's disease (CD). In many organs, fibrosis develops as a result of epithelial to mesenchymal transition (EMT). Recent studies suggested that EMT could be involved in intestinal fibr...

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Bibliographic Details
Main Authors: Michael Scharl, Nicole Huber, Silvia Lang, Alois Fürst, Ekkehard Jehle, Gerhard Rogler
Format: Article
Language:English
Published: Wiley 2015-12-01
Series:Clinical and Translational Medicine
Subjects:
Crohn's disease
Epithelial‐mesenchymal transition
Intestinal fibrosis
Online Access:https://doi.org/10.1186/s40169-015-0046-5

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