Pathological Mutations of the Mitochondrial Human Genome: the Instrumental Role of the Yeast S. cerevisiae

Mitochondrial diseases, which altogether represent not so rare diseases, can be due to mutations either in the nuclear or mitochondrial genomes. Several model organisms or cell lines are usually employed to understand the mechanisms underlying diseases, yeast being one of them. However, in the case...

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Bibliographic Details
Main Author: Monique Bolotin-Fukuhara
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Diseases
Subjects:
Online Access:http://www.mdpi.com/2079-9721/2/1/24