SARS-CoV-2 Induces Lymphocytopenia by Promoting Inflammation and Decimates Secondary Lymphoid Organs

SARS-CoV-2 Induces Lymphocytopenia by Promoting Inflammation and Decimates Secondary Lymphoid Organs

While lymphocytopenia is a common characteristic of coronavirus disease 2019 (COVID-19), the mechanisms responsible for this lymphocyte depletion are unclear. Here, we retrospectively reviewed the clinical and immunological data from 18 fatal COVID-19 cases, results showed that these patients had se...

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Bibliographic Details
Main Authors: Qun Xiang, Zeqing Feng, Bo Diao, Chao Tu, Qinghua Qiao, Han Yang, Yi Zhang, Gang Wang, Huiming Wang, Chenhui Wang, Liang Liu, Changsong Wang, Longding Liu, Rong Chen, Yuzhang Wu, Yongwen Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
macrophages
dendritic cells
lymphocytopenia
spleen
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.661052/full

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