Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update

Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update

A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias...

Full description

Bibliographic Details
Main Authors:	Hendrik S. Fischer, Nora J. Reibel, Christoph Bührer, Christof Dame
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Series:	Frontiers in Pediatrics
Subjects:	erythropoietin meta-analysis neurodevelopment neuroprotection VLBW and ELBW infants
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2021.657228/full

Similar Items

Mother-toddler play interaction in extremely, very low birth weight, and full-term children: A longitudinal study
by: Paola Salvatori, et al.
Published: (2016-09-01)

Successful conservative treatment of intestinal perforation in VLBW and ELBW neonates: a single centre case series and review of the literature
by: Nan Ye, et al.
Published: (2019-07-01)

Spontaneous Closure of the Ductus Arteriosus in Preterm Infants: A Systematic Review
by: Johan C. A. de Klerk, et al.
Published: (2020-09-01)

Early Biomarkers of Hypoxia and Inflammation and Two-Year Neurodevelopmental Outcomes in the Preterm Erythropoietin Neuroprotection (PENUT) Trial
by: Thomas R. Wood, et al.
Published: (2021-10-01)

Neuroprotective effects of erythropoietin on neurodegenerative and ischemic brain diseases: the role of erythropoietin receptor
by: Carolina Castillo Hernández, et al.
Published: (2017-01-01)

The role of early-onset-sepsis in the neurodevelopment of very low birth weight infants
by: Tjark Ortgies, et al.
Published: (2021-06-01)

Erythropoietin as a possible neuroprotective agent in patients with schizophrenia
by: George E. Barreto
Published: (2015-02-01)

Neuronal damage after moderate hypoxia and erythropoietin
by: Astrid Weber, et al.
Published: (2005-11-01)

Neuroprotective effects of erythropoietin in acute ischemic stroke
by: Bahador Asadi, et al.
Published: (2013-01-01)

Erythropoietin in ophthalmology: A literature review
by: Kaveh Abri Aghdam, et al.
Published: (2016-03-01)

Effect of early prophylactic low-dose recombinant human erythropoietin on retinopathy of prematurity in very preterm infants
by: Huiqing Sun, et al.
Published: (2020-10-01)

Erythropoietin-mediated neuroprotection in insects
by: Miljus, Natasa
Published: (2016)

Outcome of Patients With Esophageal Atresia and Very Low Birth Weight (≤ 1,500 g)
by: Laura Antonia Ritz, et al.
Published: (2020-11-01)

Neonatal Hyperglycemia Related to Parenteral Nutrition Affects Long-Term Neurodevelopment in Preterm Newborn: A Prospective Cohort Study
by: Giovanni Boscarino, et al.
Published: (2021-06-01)

Neuroprotective mechanisms of erythropoietin in a rat stroke model
by: Juenemann Martin, et al.
Published: (2020-05-01)

Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinson’s Disease
by: Federica Rey, et al.
Published: (2021-01-01)

EARLY ADMINISTRATION OF ERYTHROPOIETIN IN EXTREMELY VERY LOW BIRTH WEIGHT PRETERMS
by: Mihaela Demetrian, et al.
Published: (2019-09-01)

Predictors of early growth failure in preterm, very low birth weight infants during hospitalization
by: Noviyani Leksomono, et al.
Published: (2019-02-01)

Prolonged astrocyte-derived erythropoietin expression attenuates neuronal damage under hypothermic conditions
by: Kohki Toriuchi, et al.
Published: (2020-05-01)

Near-Infrared Spectroscopy in Extremely Preterm Infants
by: Leeann R. Pavlek, et al.
Published: (2021-01-01)

Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis
by: Ji Eun Jeong, et al.
Published: (2017-06-01)

Erythropoietin prevents necrotizing enterocolitis in very preterm infants: a randomized controlled trial
by: Yong Wang, et al.
Published: (2020-08-01)

The Orphan Cytokine Receptor CRLF3 Emerged With the Origin of the Nervous System and Is a Neuroprotective Erythropoietin Receptor in Locusts
by: Nina Hahn, et al.
Published: (2019-10-01)

The relationship between executive functioning and adaptive behavior in 2-year-old children with very low birth weight
by: Johnson, Courtney Elizabeth
Published: (2009)

Delayed erythropoietin therapy improves histological and behavioral outcomes after transient neonatal stroke
by: Amara Larpthaveesarp, et al.
Published: (2016-09-01)

The Insect Ortholog of the Human Orphan Cytokine Receptor CRLF3 Is a Neuroprotective Erythropoietin Receptor
by: Nina Hahn, et al.
Published: (2017-07-01)

Recognition and characterization of Erythropoietin binding-proteins in the brain of mice
by: Reza Kowsari, et al.
Published: (2016-09-01)

Neonatal Magnesium Levels Correlate with Motor Outcomes in Premature Infants: a Long-Term Retrospective Cohort Study
by: Elizabeth eDoll, et al.
Published: (2014-11-01)

Effects of erythropoietin on neurological performance of patients with traumatic brain injury: a systematic literature review
by: Gholamreza Bahadorkhan, et al.
Published: (2017-01-01)

Exploring Erythropoietin and G-CSF Combination Therapy in Chronic Stroke Patients
by: Yoon-Kyum Shin, et al.
Published: (2016-03-01)

Interplay between Endothelin and Erythropoietin in Astroglia: The Role in Protection against Hypoxia
by: Richard Schäfer, et al.
Published: (2014-02-01)

Effect of Protein Supplementation on the Growth of Infants Weighing Less than 1,000 Grams Hospitalized on the Neonatal Intensive Care Unit of Akbar Abadi Hospital in Tehran, Iran (2015-2016)
by: Mandana Kashaki, et al.
Published: (2018-09-01)

A Rare Case of Accidental Esophageal Perforation in an Extremely Low Birth Weight Neonate
by: Pradeep Suryawanshi, et al.
Published: (2014-06-01)

Growth and Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants: A Single Center’s Experience
by: Yung-Chieh Lin, et al.
Published: (2011-12-01)

Improving clinical outcomes of very low birth weight infants: Implementation of standardized management guidelines in tertiary care hospital in Haryana
by: Sunaina Arora, et al.
Published: (2020-12-01)

Upregulation of erythropoietin and erythropoietin receptor in castration-resistant progression of prostate cancer
by: Chen Ye, et al.
Published: (2020-01-01)

The assessment of native erythropoietin and antibodies to recombinant erythropoietin in haemodialysis patients
by: Benjamin, Sherilene Cheryl
Published: (2008)

The assessment of native erythropoietin and antibodies to recombinant erythropoietin in haemodialysis patients
by: Benjamin, Sherilene Cheryl
Published: (2008)

Clinical and Nutritional Determinants of Extrauterine Growth Restriction Among Very Low Birth Weight Infants
by: Khasawneh W, et al.
Published: (2020-11-01)

Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor
by: Hellewell, Sarah, et al.
Published: (2013)