diffReps: detecting differential chromatin modification sites from ChIP-seq data with biological replicates.

ChIP-seq is increasingly being used for genome-wide profiling of histone modification marks. It is of particular importance to compare ChIP-seq data of two different conditions, such as disease vs. control, and identify regions that show differences in ChIP enrichment. We have developed a powerful a...

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Bibliographic Details
Main Authors: Li Shen, Ning-Yi Shao, Xiaochuan Liu, Ian Maze, Jian Feng, Eric J Nestler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677880?pdf=render

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