diffReps: detecting differential chromatin modification sites from ChIP-seq data with biological replicates.
ChIP-seq is increasingly being used for genome-wide profiling of histone modification marks. It is of particular importance to compare ChIP-seq data of two different conditions, such as disease vs. control, and identify regions that show differences in ChIP enrichment. We have developed a powerful a...
Main Authors: | Li Shen, Ning-Yi Shao, Xiaochuan Liu, Ian Maze, Jian Feng, Eric J Nestler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3677880?pdf=render |
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