Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

<p>Abstract</p> <p>Background</p> <p>The NV1020 oncolytic herpes simplex virus type-1 has shown significant promise for the treatment of many different types of tumors in experimental animal models and human trials. Previously, we described the construction and use of t...

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Bibliographic Details
Main Authors:	David Andrew T, Baghian Abolghasem, Chouljenko Vladimir N, Israyelyan Anna, Kearney Michael T, Kousoulas Konstantin G
Format:	Article
Language:	English
Published:	BMC 2008-06-01
Series:	Virology Journal
Online Access:	http://www.virologyj.com/content/5/1/68

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