Review of the Reported Measures of Clinical Validity and Clinical Utility as Arguments for the Implementation of Pharmacogenetic Testing: A Case Study of Statin-Induced Muscle Toxicity

Review of the Reported Measures of Clinical Validity and Clinical Utility as Arguments for the Implementation of Pharmacogenetic Testing: A Case Study of Statin-Induced Muscle Toxicity

Advances from pharmacogenetics (PGx) have not been implemented into health care to the expected extent. One gap that will be addressed in this study is a lack of reporting on clinical validity and clinical utility of PGx-tests. A systematic review of current reporting in scientific literature was co...

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Bibliographic Details
Main Authors: Marleen E. Jansen, T. Rigter, W. Rodenburg, T. M. C. Fleur, E. J. F. Houwink, M. Weda, Martina C. Cornel
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
clinical validity
clinical utility
pharmacogenetics
statins
translation
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00555/full

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